I’m using Gmail to handle all my domain email. With 4.7GB of space for every account I create, I can access my email from anywhere with Internet access or via my Helio Ocean, take advantage of Gmail’s search capabilities and spam filters, and count on Gmail’s reliability and uptime.
The mail service my hosting provider offers has actually gone down a couple times over the past several years and did nothing to combat the spam issue. Whenever I’m away I’ve had to log on to delete spam messages so that my 10MB mailboxes don’t fill up while I’m away. Plus the recent upgrade of my hosting provider’s system took away the catch-all email address feature that enabled me to personalize email addresses for different sites.
Making the switch was relatively painless and easy, and so far it’s been working great. I’ve been getting 200+ spam messages a day, all of them caught by Gmail’s filters except maybe 1 spam message every couple days. The false positives have been even less frequent. Of course, it took me a while to get used to this; I’d been accustomed to having mail messages to download to Thunderbird every time I checked mail, even if they were all spam. When this stopped being the case, I worried that I’d fucked something up in the setup, when in fact there just wasn’t any new legitimate email.
Other Google Apps are also available for your domain if you choose to turn them on: Google Calendar, Google Talk, Google Docs and Spreadsheets, and Google Start Page.